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fibroblast growth factor 2  (R&D Systems)


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    R&D Systems fibroblast growth factor 2
    Fibroblast Growth Factor 2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fibroblast growth factor 2/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    fibroblast growth factor 2 - by Bioz Stars, 2026-04
    96/100 stars

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    Arecoline-induced fibrosis in hOMF cells. (A) Experimental design flowchart; (B) Effects of different doses of arecoline on hOMF cell viability at 24h ( x ¯ ±s, n = 3); (C) Effects of different doses of arecoline on hOMF cell viability at 48h ( x ¯ ±s, n = 3); (D) Effects of different doses of arecoline on hOMF cell viability at 72h ( x ¯ ±s, n = 3); (E) Immunofluorescence staining of α-SMA expression in hOMF cells treated with arecoline (n = 3); (200x); (F) Immunofluorescence staining of Col1a1 expression in hOMF cells treated with arecoline (n = 3); (200x); (G) Quantitative analysis of α-SMA fluorescence intensity ( x ¯ ± s , n = 3); (H) Quantitative analysis of Col1a1 fluorescence intensity ( x ¯ ±s, n = 3). (I) Protein expression levels of <t>bFGF</t> ( x ¯ ±s, n = 3); (J) Protein expression levels <t>of</t> <t>TGF-β1</t> ( x ¯ ±s, n = 3); (K) Relative mRNA expression levels of YAP ( x ¯ ±s, n = 3); (L) Relative mRNA expression levels of TAZ ( x ¯ ±s, n = 3). Compared with the Control group, * P < 0.05, ** P < 0.01.
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    Arecoline-induced fibrosis in hOMF cells. (A) Experimental design flowchart; (B) Effects of different doses of arecoline on hOMF cell viability at 24h ( x ¯ ±s, n = 3); (C) Effects of different doses of arecoline on hOMF cell viability at 48h ( x ¯ ±s, n = 3); (D) Effects of different doses of arecoline on hOMF cell viability at 72h ( x ¯ ±s, n = 3); (E) Immunofluorescence staining of α-SMA expression in hOMF cells treated with arecoline (n = 3); (200x); (F) Immunofluorescence staining of Col1a1 expression in hOMF cells treated with arecoline (n = 3); (200x); (G) Quantitative analysis of α-SMA fluorescence intensity ( x ¯ ± s , n = 3); (H) Quantitative analysis of Col1a1 fluorescence intensity ( x ¯ ±s, n = 3). (I) Protein expression levels of bFGF ( x ¯ ±s, n = 3); (J) Protein expression levels of TGF-β1 ( x ¯ ±s, n = 3); (K) Relative mRNA expression levels of YAP ( x ¯ ±s, n = 3); (L) Relative mRNA expression levels of TAZ ( x ¯ ±s, n = 3). Compared with the Control group, * P < 0.05, ** P < 0.01.

    Journal: Frontiers in Physiology

    Article Title: Uncovering the mechanism of arecoline’s effect on oral submucous fibrosis: integrating transcriptomics and in vitro and in vivo experiments

    doi: 10.3389/fphys.2026.1768602

    Figure Lengend Snippet: Arecoline-induced fibrosis in hOMF cells. (A) Experimental design flowchart; (B) Effects of different doses of arecoline on hOMF cell viability at 24h ( x ¯ ±s, n = 3); (C) Effects of different doses of arecoline on hOMF cell viability at 48h ( x ¯ ±s, n = 3); (D) Effects of different doses of arecoline on hOMF cell viability at 72h ( x ¯ ±s, n = 3); (E) Immunofluorescence staining of α-SMA expression in hOMF cells treated with arecoline (n = 3); (200x); (F) Immunofluorescence staining of Col1a1 expression in hOMF cells treated with arecoline (n = 3); (200x); (G) Quantitative analysis of α-SMA fluorescence intensity ( x ¯ ± s , n = 3); (H) Quantitative analysis of Col1a1 fluorescence intensity ( x ¯ ±s, n = 3). (I) Protein expression levels of bFGF ( x ¯ ±s, n = 3); (J) Protein expression levels of TGF-β1 ( x ¯ ±s, n = 3); (K) Relative mRNA expression levels of YAP ( x ¯ ±s, n = 3); (L) Relative mRNA expression levels of TAZ ( x ¯ ±s, n = 3). Compared with the Control group, * P < 0.05, ** P < 0.01.

    Article Snippet: Primers were designed by Wuhan Kingwell Biotechnology Co., Ltd. TGF-β (E-EL-0162) and bFGF (E-EL-H6042) ELISA kits, as well as the Enhanced Cell Counting Kit 8 (WST-8/CCK8) (E-CK-A362), were purchased from Elabscience Biotechnology (Wuhan, China).

    Techniques: Immunofluorescence, Staining, Expressing, Fluorescence, Control